Natural Products and Extracts as Xantine Oxidase Inhibitors – A Hope for Gout Disease?

This was just published in Current Pharmaceutical Design:

Xanthine oxidase (EC 1.17.3.2) (XO) is among the main enzymatic sources that produce reactive oxygen species (ROS) in the living system. It is a dehydrogenase enzyme that performs electron transfer to nicotinamide adenine dinucleotide (NAD+ ), while oxidizing hypoxanthin, which is an intermediate substance in purine catabolism, first to xanthine and then to uric acid. XO becomes an oxidant enzyme that oxidizes thiol groups under certain stress conditions in the tissue. The last metabolic step, in which hypoxanthin becomes uric acid, is catalyzed by XO. Uric acid, considered a waste product, can cause kidney stones and gouty-type arthritis as it is taken shape, when present in high concentrations. Therefore, XO inhibitors are one of the drug classes utilized against gout, a purine metabolic process disease that causes urate crystal storage in the joint and its environments triggered by hyperuricemia. Urate-lowering treatment consist of XO inhibitors that decrease uric acid production as well as uricosuric drugs that increase urea excretion. Current drugs that block uric acid synthesis through XO inhibition are uricase, allopurinol, and febuxostat. Considering that the side results, security and tolerability issues of some current gout medications still exist; intensive research study is ongoing to look for new, reliable, and safer XO inhibitors of synthetic or natural origins for the treatment of the disease. In the present evaluation, we aimed to examine in information XO inhibitory capacities of pure natural substances along with the extracts from plants and other natural sources through screening Pubmed, Web of Science (WoS), Scopus, and Google Academic. The data mentioned to the reality that natural items, especially phenolics such as flavonoids (quercetin, apigenin, and scutellarein), tannins (agrimoniin and ellagitannin), chalcones (melanoxethin), triterpenes (ginsenoside Rd and ursolic acid), stilbenes (resveratrol and piceatannol), alkaloids (berberin and palmatin) have a great prospective for new XO inhibitors efficient in usage against gout disease. In addition, not just plants however other biological sources such as microfungi, macrofungi, lichens, bugs (silk worms, ants, etc) appear to be the appealing sources of novel XO inhibitors.

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Bestseller No. 1
Purge! Uric Acid Cleanse & Joint Support – Ready to Eat & Drink What You Want? – Active Mobility, Strong Flexibility, Healthy Inflammation – Tart Cherry & Celery Seed – 60 Vegetarian Soft Capsules
  • Joint comfort and detoxification promote healthy uric acid levels and maintain proper balance. You can have the confidence that every capsule has the strength and potency needed for uric acid support.
  • We blend all our products at a cGMP Certified Laboratory to ensure a contaminant-free product. We wouldn't have it any other way and neither should you.
  • Super ingredients rich in anthocyanins and antioxidants like Celery Seed and Tart Cherry Extract, Purge naturally promotes joint health, providing you with the best power to maintain comfort, flexibility, and mobility.
  • Pure natural formula in 100% vegetarian easy-to-swallow soft capsules, completely free of fillers, binders, and artificial ingredients. No gluten, wheat, or dairy. And of course, never tested on animals. Just a pure and tested product.
  • Try our products without worry with our 100% Happiness & Heath Commitment. We're confident that you will see results and be thrilled with your purchase. And through our Vitamin Angels 1-for-1 Match program, one bottle equals one year of vitamins for a child in need.
SaleBestseller No. 2
Uric Acid Cleanse with Tart Cherry 9600mg - Made in USA - Clinically Proven Natural Gоut Relief - Joint Comfort & Detoxification - Liquid Uric Acid Support Formula for High BioAvailability
  • Uric Acid Level Control - Concentrated Herbal Complex includes the right powerful mix of ingredients such as Tart Cherry & Celery Seed, which is clinically proven to support your healthy joints and uric acid balance in your system. This is the most efficient Uric Acid Level Control with 9600 mg Tart Cherry infused.
  • Max Absorption & Rapid Recovery - Our Uric Acid Cleanse with celery seed, as supporting ingredient, delivers potent anthocyanins to achieve joint comfort and recover muscles. The powerful combination provides joints with the ability to maintain comfort & flexibility naturally.
  • Strong Antioxidant Effect - The Unique Blend of Active Ingredients full of Vitamins & Trace Minerals, perfect for your health. Moreover, Polyphenols in Tart Cherry have more antioxidants than any other product. They protect your muscles from oxidative damage, support strength, and provide long-term wellness.
  • Pure Natural Formula - FairMile Organics is the most refined nutrition brand using zero fillers, binders, or artificial ingredients. We manufacture our product in the USA. Our tincture is gluten, wheat & dairy-free, and was never tested on animals.
  • Health Improvements & Satisfaction Guarantee - Be sure: you're fueling your body with the very best. We're confident that you will see results and be thrilled with your purchase. Otherwise, we are open to your proposals. Any of your questions will be resolved by professional customer service.
Bestseller No. 3
Uric Acid Support Supplement – Go-Out Tart Cherry Extract Capsules for SUSTAINED Relief, Improved Joint Health & Circulation with Celery Seed Extract, Turmeric, Bromelain by Mt. Angel Vitamins, 90-Ct.
  • LIVE LIVELY – Don’t let discomfort ruin your day. Ease joint pain and enjoy activities with Mt. Angel Vitamins! Go-Out uric acid cleanse provides sustained relief so you can get back on your feet!
  • IMPROVE & MOVE – Sick of stiffness? Help restore joint flexibility with black and tart cherry extract, celery seed extract, bromelain, and turmeric root. Go with go out capsules formulated with ingredients known to reduce inflammation.
  • GO WITH THE FLOW – By lowering uric acid levels, your go out relief capsules are known to fortify healthy circulation and blood pressure, protecting muscles and joints from damage.
  • SIMPLE SOLUTION – Enjoy a supplement that works with your schedule! To free yourself from pain, just take 1 of your 90 inflammation relief capsules twice daily. Support has never been so simple!
  • OUR PROMISE – At Mt. Angel Vitamins, we take pride in our capsules’ quality. We ensure your positive experience with restorative results from personally crafted and tested, non-GMO supplements!
Bestseller No. 4
Therapeutic Gout Relief Cream with Arnica Extract, Ilex Leaf Extract, Aloe Vera and Tea Tree Oil.
  • Immediate, Lasting & Quick Relief: Did you know that our unique pain relief cream is preferred by those dealing with inflammation, pain and discomfort related to flare-ups? Numerous All Natural pain relievers go to work to reduce inflammation, provide soothing relief and get you back on your feet!
  • Non-Greasy, Non-Staining & Fast Absorbing: Arnica gel cream with a refreshing mint scent. Within minutes, the cream is absorbed and the scent is vanished. Get back to your normal life!
  • Made In The USA: Manufactured and Packaged in the USA in a GMP Approved Facility for Purity and Potency
  • Natural Ingredients: Include Arnica Extract, Tea Tree Oil, Ilex Leaf Extract, Aloe, vitamins E & B6 and MSM.
  • Money Back Guarantee: We stand behind our Therapeutic Pain Relief Cream 100% and are sure you are going to love it! If you are less than 100% Satisfied with our product, for ANY reason, we will refund your money in full with no questions asked. What do you have to lose? Buy Now!
SaleBestseller No. 5
The Healing Gout Cookbook: Anti-Inflammatory Recipes to Lower Uric Acid Levels and Reduce Flares
  • Andrews MEd RD LD, Lisa Cicciarello (Author)
  • English (Publication Language)
  • 158 Pages - 03/31/2020 (Publication Date) - Rockridge Press (Publisher)
Bestseller No. 6
Urcinol - The Leading Uric Acid Supplement - 30 Day Supply. Premium Pain Relief & More Powerful Than Tart Cherry at Flushing Out Uric Acid.
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
Bestseller No. 7
NutriGout - Uric Acid Support Formula - 60 Vegetarian Capsules
  • Get Your Life Back - Sudden, severe pain caused by uric acid buildup strikes at the most unpredictable times. Take back control with NutriGout so you can do the things you love again
  • Stops Pain Before It Begins - Our uric acid supplement supports your kidneys and liver so that your body naturally flushes out excess uric acid before it gets out of control
  • All Natural Relief - Turmeric, Milk Thistle Extract, Bromelain, Celery Seed, Dandelion Extract and Chanca Piedra work synergistically, supporting normal, healthy UA levels
  • Made In The USA - Inspected in a GMP certified laboratory, our GMO-free formula contains no artificial colors or flavors. Powerful antioxidants can help restore joint flexibility, making it easier to rise out of bed in the morning and tackle your day
  • Need To Try It Before You Commit? We Guarantee your results, or your money back. So go ahead and click add to cart - your joints will thank you!
SaleBestseller No. 8
Uricel The Best Uric Acid Support Formula - High Potency Advanced Key Ingredients Designed to Support Healthy Uric Acid Levels with Tart Cherry, Celery Seed and More
  • TINGLE-FREE FEET & TOES. Uricel is a fast-acting herbal uric acid cleanse that helps balance uric acid levels to melt away the sharp tingling feeling in your feet and toes. By giving your body exactly what it needs to help expel the excess Uric acid which causes discomfort, the body can then do what it does best by helping return you get back to your normal self.
  • CLEANSE AND FLUSH URIC ACID and uric acid crystals that aggravate your feet, toes, and joints. Uricel is an herbal blend of Tart Cherry, Chanca Piedra, and Celery Seed that helps balance uric acid levels to target swelling and avoid future flare-ups. Our customers are constantly amazed by just how fast their discomfort in their feet, toes, and other affected joints melts away. Uricel is designed to help you regain your mobility and continue with your daily routines as quickly as possible.
  • SUPPORTS HEALTHY KIDNEYS, TOO. Purine content from diet and alcohol can form uric acid crystals that are difficult for your kidneys to pass. Chanca Piedrea translates to “stone breaker,” and Celery Seed is a mild diuretic that boosts urine flow to get uric acid moving out of the body and support healthy kidneys.
  • CAPSULES NEED TO BE DIGESTED, LIQUIDS DON’T. Have you ever seen a pill in nature? Neither have we, and frankly, we're tired of the nasty burps and eye-watering gulps. Liquids don't need to travel to your stomach before they start absorbing, liquids are immediately bioavailable and work fast! Not to mention, our alcohol-free tinctures taste great, and they're safe for kids, too.
  • CRAFTED UNDER THE GUIDANCE OF A TRAINED HERBALIST IN THE USA. Instead of cramming all these ingredients in a capsule that was thrown together somewhere in China, Uricel is made and manufactured in the USA. Each batch is 3rd-party tested for safety and purity so you only get the best.
Bestseller No. 9
Gout Complete 16oz - Natural & Organic Liquid Gout Treatment, Uric Acid Flush & Remedy Support Medicine (W/Tart Cherry)
  • WHY USE A LIQUID TREATMENT? – Research indicates that liquid supplements are more easily absorbed into the body. With an average absorption rate of better than 90% vs. pills at 10-15%, doesn’t it make sense that a liquid can control uric acid better and is the best alternative? Pills using the best of ingredients are simply less effective for relief.
  • PROVEN RESULTS – As a naturopathic remedy using only natural and organic ingredients, we addressed the root causes of uric acid buildup, kidney function and circulation. With proven ingredients that address kidney function, inflammation, pain, circulation, and many other health specific issues that take place to create the imbalance of uric acid in the body, these natural remedies are for you. Uric Acid Complete is used both during the course of an attack and as a preventative measure.
  • A COMPLETE ALTERNATIVE – With both Organic and Kosher certifications, we use only the highest concentration and quality of ingredients. We use more than 35 ingredients, 3 times more than any comparable product, to help reduce inflammation, increase circulation, cleanse and flush out infection, and rebalance Ph, mineral and uric acid levels. With our 100% SATISFACTION GUARANTEE, you can feel safe that you are making the best choice in a proven and natural uric acid reducer.
  • MADE IN THE USA! USDA Organic and OU Kosher Certified.
Bestseller No. 10
The 28-Day Gout Diet Plan: The Optimal Nutrition Guide to Manage Gout
  • Kamveris MS RD LDN, Sophia (Author)
  • English (Publication Language)
  • 194 Pages - 02/05/2019 (Publication Date) - Rockridge Press (Publisher)

I get commissions for purchases made through links on this website. As an Amazon Associate I earn from qualifying purchases.

Colchicine, a common drug to treat gout, is being evaluated to treat COVID-19 and shows significant reduction in inflammation and lung injury in pre-clinical studies

Death in COVID-19 patients has actually been linked to the cytokine storm, where the body produces excessive pro-inflammatory particles (cytokines) that ultimately lead to ARDS and potentially death. Full research study outcomes are readily available in preprint and support the continuation of the COLCORONA trial.

The double-blind, placebo-controlled, randomized COLCORONA trial featuring a generic immunomodulator (colchicine) passed its futility analysis in June 2020 with an independent Data Safety Monitoring Board, enabling continued enrollment. Colchicine, which is already available for treatment of gout, pericarditis, and Familial Mediterranean Fever, would be a cost effective orally administered treatment alternative if outcomes prove positive..

Unlike most other research studies, this research study does not include leaving your house. The study staff will call you straight via phone or video-visits for follow-up. Medication or a placebo (a pill without any active components) will be provided to your house at no cost.If you have an interest in signing up with, the study personnel will figure out if you are eligible to join. This research study is among the couple of registering newly detected patients with moderate to moderate signs who are not hospitalized and over the age of 40 (and hires clients past the age of 70). Involvement in the research study lasts 30 days. When the research study is completed, the results will be announced, however will not include your recognizing information.Patients and physicians thinking about COLCORONA can call the research study hotline at 1-877-536-6837, 24/7 or visit www.colcorona.net. If you have actually recently been detected with COVID-19 and you are interested in taking part in the COLCORONA trial, do not postpone calling the hotline number.

The COLCORONA trial hires recently diagnosed, non-hospitalized adult clients with COVID-19 for participation in a totally free, at-home clinical trial developed to minimally problem patients. Full research study outcomes are available in preprint and support the extension of the COLCORONA trial.

What Patients Need to Know About the COLCORONA Trial to Enroll.

” At the minute, there is no readily available, FDA-approved treatment that can be provided to patients in your home to avoid them from getting worse health problem, hospitalization and death from COVID-19 problems. It is extremely crucial for us to discover therapies that we can provide to clients now,” stated Dr. Norman Lepor, Director of Clinical Research for Westside Medical Associates of Los Angeles and COLCORONA main investigator for Los Angeles.

About the COLCORONA Trial.

Unlike many other research studies, this study does not involve leaving your home. If you have actually recently been detected with COVID-19 and you are interested in getting involved in the COLCORONA trial, do not delay calling the hotline number.

MONTREAL, July 27, 2020 / PRNewswire/– Montreal Heart Institute (MHI) today revealed that the COLCORONA scientific trial has actually increased registration capability in the United States ( Los Angeles, San Francisco, Houston, Dallas, Miami, Gainesville, New York, New Jersey, Connecticut) as the favorable case numbers of COVID-19 continue to rise. The COLCORONA trial hires recently diagnosed, non-hospitalized adult patients with COVID-19 for participation in a free, at-home clinical trial created to minimally burden clients. The largest trial of its kind, this at-home, contactless trial continues to likewise register in Canada, Spain and South Africa with more sites constantly added.

” Our current lead to pre-clinical research studies reveal the capacity of colchicine to minimize the inflammatory storm and lung damage likewise seen in clients with COVID-19,” said Dr. Jean-Claude Tardif, Director of the Research Center at MHI, Professor of Medicine at the University of Montreal, and COLCORONA principal detective. “We are dedicated to consisting of a large number of patients worldwide in this robust research study to determine the capability of colchicine to keep clients out of the healthcare facility, off ventilators and ultimately save lives.”

COLCORONA is a contact-free, at-home, randomized, double-blind, placebo-controlled study lack numerous areas in Canada, the United States, Europe, South America, and South Africa. COLCORONA is collaborated by the Montreal Health Innovations Coordinating Center (MHICC) and moneyed by the Government of Quebec, the Bill & & Melinda Gates Foundation, the National Heart, Lung, and Blood Institute (NHLBI) of the United States National Institutes of Health (NIH), and Sophie Desmarais Montréal benefactor, daughter of the late company mogul, Paul Desmarais Sr., Pharmascience, CGI, and DACIMA are likewise collaborators of COLCORONA.

To learn more about the study, go to www.colcorona.net.

Advertisement:

Bestseller No. 1
Purge! Uric Acid Cleanse & Joint Support – Ready to Eat & Drink What You Want? – Active Mobility, Strong Flexibility, Healthy Inflammation – Tart Cherry & Celery Seed – 60 Vegetarian Soft Capsules
  • Joint comfort and detoxification promote healthy uric acid levels and maintain proper balance. You can have the confidence that every capsule has the strength and potency needed for uric acid support.
  • We blend all our products at a cGMP Certified Laboratory to ensure a contaminant-free product. We wouldn't have it any other way and neither should you.
  • Super ingredients rich in anthocyanins and antioxidants like Celery Seed and Tart Cherry Extract, Purge naturally promotes joint health, providing you with the best power to maintain comfort, flexibility, and mobility.
  • Pure natural formula in 100% vegetarian easy-to-swallow soft capsules, completely free of fillers, binders, and artificial ingredients. No gluten, wheat, or dairy. And of course, never tested on animals. Just a pure and tested product.
  • Try our products without worry with our 100% Happiness & Heath Commitment. We're confident that you will see results and be thrilled with your purchase. And through our Vitamin Angels 1-for-1 Match program, one bottle equals one year of vitamins for a child in need.
SaleBestseller No. 2
Uric Acid Cleanse with Tart Cherry 9600mg - Made in USA - Clinically Proven Natural Gоut Relief - Joint Comfort & Detoxification - Liquid Uric Acid Support Formula for High BioAvailability
  • Uric Acid Level Control - Concentrated Herbal Complex includes the right powerful mix of ingredients such as Tart Cherry & Celery Seed, which is clinically proven to support your healthy joints and uric acid balance in your system. This is the most efficient Uric Acid Level Control with 9600 mg Tart Cherry infused.
  • Max Absorption & Rapid Recovery - Our Uric Acid Cleanse with celery seed, as supporting ingredient, delivers potent anthocyanins to achieve joint comfort and recover muscles. The powerful combination provides joints with the ability to maintain comfort & flexibility naturally.
  • Strong Antioxidant Effect - The Unique Blend of Active Ingredients full of Vitamins & Trace Minerals, perfect for your health. Moreover, Polyphenols in Tart Cherry have more antioxidants than any other product. They protect your muscles from oxidative damage, support strength, and provide long-term wellness.
  • Pure Natural Formula - FairMile Organics is the most refined nutrition brand using zero fillers, binders, or artificial ingredients. We manufacture our product in the USA. Our tincture is gluten, wheat & dairy-free, and was never tested on animals.
  • Health Improvements & Satisfaction Guarantee - Be sure: you're fueling your body with the very best. We're confident that you will see results and be thrilled with your purchase. Otherwise, we are open to your proposals. Any of your questions will be resolved by professional customer service.
Bestseller No. 3
Uric Acid Support Supplement – Go-Out Tart Cherry Extract Capsules for SUSTAINED Relief, Improved Joint Health & Circulation with Celery Seed Extract, Turmeric, Bromelain by Mt. Angel Vitamins, 90-Ct.
  • LIVE LIVELY – Don’t let discomfort ruin your day. Ease joint pain and enjoy activities with Mt. Angel Vitamins! Go-Out uric acid cleanse provides sustained relief so you can get back on your feet!
  • IMPROVE & MOVE – Sick of stiffness? Help restore joint flexibility with black and tart cherry extract, celery seed extract, bromelain, and turmeric root. Go with go out capsules formulated with ingredients known to reduce inflammation.
  • GO WITH THE FLOW – By lowering uric acid levels, your go out relief capsules are known to fortify healthy circulation and blood pressure, protecting muscles and joints from damage.
  • SIMPLE SOLUTION – Enjoy a supplement that works with your schedule! To free yourself from pain, just take 1 of your 90 inflammation relief capsules twice daily. Support has never been so simple!
  • OUR PROMISE – At Mt. Angel Vitamins, we take pride in our capsules’ quality. We ensure your positive experience with restorative results from personally crafted and tested, non-GMO supplements!
Bestseller No. 4
Therapeutic Gout Relief Cream with Arnica Extract, Ilex Leaf Extract, Aloe Vera and Tea Tree Oil.
  • Immediate, Lasting & Quick Relief: Did you know that our unique pain relief cream is preferred by those dealing with inflammation, pain and discomfort related to flare-ups? Numerous All Natural pain relievers go to work to reduce inflammation, provide soothing relief and get you back on your feet!
  • Non-Greasy, Non-Staining & Fast Absorbing: Arnica gel cream with a refreshing mint scent. Within minutes, the cream is absorbed and the scent is vanished. Get back to your normal life!
  • Made In The USA: Manufactured and Packaged in the USA in a GMP Approved Facility for Purity and Potency
  • Natural Ingredients: Include Arnica Extract, Tea Tree Oil, Ilex Leaf Extract, Aloe, vitamins E & B6 and MSM.
  • Money Back Guarantee: We stand behind our Therapeutic Pain Relief Cream 100% and are sure you are going to love it! If you are less than 100% Satisfied with our product, for ANY reason, we will refund your money in full with no questions asked. What do you have to lose? Buy Now!
SaleBestseller No. 5
The Healing Gout Cookbook: Anti-Inflammatory Recipes to Lower Uric Acid Levels and Reduce Flares
  • Andrews MEd RD LD, Lisa Cicciarello (Author)
  • English (Publication Language)
  • 158 Pages - 03/31/2020 (Publication Date) - Rockridge Press (Publisher)
Bestseller No. 6
Urcinol - The Leading Uric Acid Supplement - 30 Day Supply. Premium Pain Relief & More Powerful Than Tart Cherry at Flushing Out Uric Acid.
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
Bestseller No. 7
NutriGout - Uric Acid Support Formula - 60 Vegetarian Capsules
  • Get Your Life Back - Sudden, severe pain caused by uric acid buildup strikes at the most unpredictable times. Take back control with NutriGout so you can do the things you love again
  • Stops Pain Before It Begins - Our uric acid supplement supports your kidneys and liver so that your body naturally flushes out excess uric acid before it gets out of control
  • All Natural Relief - Turmeric, Milk Thistle Extract, Bromelain, Celery Seed, Dandelion Extract and Chanca Piedra work synergistically, supporting normal, healthy UA levels
  • Made In The USA - Inspected in a GMP certified laboratory, our GMO-free formula contains no artificial colors or flavors. Powerful antioxidants can help restore joint flexibility, making it easier to rise out of bed in the morning and tackle your day
  • Need To Try It Before You Commit? We Guarantee your results, or your money back. So go ahead and click add to cart - your joints will thank you!
SaleBestseller No. 8
Uricel The Best Uric Acid Support Formula - High Potency Advanced Key Ingredients Designed to Support Healthy Uric Acid Levels with Tart Cherry, Celery Seed and More
  • TINGLE-FREE FEET & TOES. Uricel is a fast-acting herbal uric acid cleanse that helps balance uric acid levels to melt away the sharp tingling feeling in your feet and toes. By giving your body exactly what it needs to help expel the excess Uric acid which causes discomfort, the body can then do what it does best by helping return you get back to your normal self.
  • CLEANSE AND FLUSH URIC ACID and uric acid crystals that aggravate your feet, toes, and joints. Uricel is an herbal blend of Tart Cherry, Chanca Piedra, and Celery Seed that helps balance uric acid levels to target swelling and avoid future flare-ups. Our customers are constantly amazed by just how fast their discomfort in their feet, toes, and other affected joints melts away. Uricel is designed to help you regain your mobility and continue with your daily routines as quickly as possible.
  • SUPPORTS HEALTHY KIDNEYS, TOO. Purine content from diet and alcohol can form uric acid crystals that are difficult for your kidneys to pass. Chanca Piedrea translates to “stone breaker,” and Celery Seed is a mild diuretic that boosts urine flow to get uric acid moving out of the body and support healthy kidneys.
  • CAPSULES NEED TO BE DIGESTED, LIQUIDS DON’T. Have you ever seen a pill in nature? Neither have we, and frankly, we're tired of the nasty burps and eye-watering gulps. Liquids don't need to travel to your stomach before they start absorbing, liquids are immediately bioavailable and work fast! Not to mention, our alcohol-free tinctures taste great, and they're safe for kids, too.
  • CRAFTED UNDER THE GUIDANCE OF A TRAINED HERBALIST IN THE USA. Instead of cramming all these ingredients in a capsule that was thrown together somewhere in China, Uricel is made and manufactured in the USA. Each batch is 3rd-party tested for safety and purity so you only get the best.
Bestseller No. 9
Gout Complete 16oz - Natural & Organic Liquid Gout Treatment, Uric Acid Flush & Remedy Support Medicine (W/Tart Cherry)
  • WHY USE A LIQUID TREATMENT? – Research indicates that liquid supplements are more easily absorbed into the body. With an average absorption rate of better than 90% vs. pills at 10-15%, doesn’t it make sense that a liquid can control uric acid better and is the best alternative? Pills using the best of ingredients are simply less effective for relief.
  • PROVEN RESULTS – As a naturopathic remedy using only natural and organic ingredients, we addressed the root causes of uric acid buildup, kidney function and circulation. With proven ingredients that address kidney function, inflammation, pain, circulation, and many other health specific issues that take place to create the imbalance of uric acid in the body, these natural remedies are for you. Uric Acid Complete is used both during the course of an attack and as a preventative measure.
  • A COMPLETE ALTERNATIVE – With both Organic and Kosher certifications, we use only the highest concentration and quality of ingredients. We use more than 35 ingredients, 3 times more than any comparable product, to help reduce inflammation, increase circulation, cleanse and flush out infection, and rebalance Ph, mineral and uric acid levels. With our 100% SATISFACTION GUARANTEE, you can feel safe that you are making the best choice in a proven and natural uric acid reducer.
  • MADE IN THE USA! USDA Organic and OU Kosher Certified.
Bestseller No. 10
The 28-Day Gout Diet Plan: The Optimal Nutrition Guide to Manage Gout
  • Kamveris MS RD LDN, Sophia (Author)
  • English (Publication Language)
  • 194 Pages - 02/05/2019 (Publication Date) - Rockridge Press (Publisher)

I get commissions for purchases made through links on this website. As an Amazon Associate I earn from qualifying purchases.

Revive Therapeutics Explores the Use of Bucillamine as a Novel Treatment for Infectious Diseases including COVID-19

” Revive was founded on the facility of finding brand-new uses for known drugs, and we are broadening on our rich item portfolio to target transmittable diseases such as the coronavirus illness or COVID-19,” stated Michael Frank, Revives Chief Executive Officer. “Revive has a history in the medical advancement with Bucillamine in the treatment of intense gout flares and cystinuria, and we will advance our efforts in restoring and checking out new usages of Bucillamine for unmet medical requirements.”

TORONTO, March 20, 2020 (WORLD NEWSWIRE)– Revive Therapies Ltd. (” Revive” or the “Business”) (CSE: RVV), a life sciences business, is delighted to reveal that it is checking out making use of the drug Bucillamine as a prospective novel treatment for contagious diseases including influenza and the coronavirus illness (COVID-19). The Business has actually requested a provisionary patent with the U.S. Patent and Trademark Office entitled “Use of Bucillamine in the Treatment of Contagious Diseases” (Serial No. 62/991,996).

Restore has explored making use of Bucillamine in the treatment of severe gout flares and has completed a Phase 2 research study in the U.S. under its Investigational New Drug (” IND”) application that was accepted by the U.S. Food and Drug Administration (” FDA”). The Company checked out the usage of Bucillamine in the treatment of cystinuria where it has actually received FDA orphan drug status and its IND was accepted by the FDA to perform a Phase 2 research study in the U.S.

Scientific Rationale for the Investigation reasoning Bucillamine to Treat Infectious Diseases including Influenza transmittable COVID-19

Bucillamine (N-( mercapto-2-methylpropionyl)- l-cysteine), which has a widely known security profile and is recommended in the treatment of rheumatoid arthritis in Japan and South Korea for over 30 years, is a cysteine derivative with 2 thiol groups that is 16-fold more powerful than NAC as a thiol donor in vivo, providing it greatly remarkable function in bring back glutathione and for that reason greater potential to avoid intense lung injury during influenza infection.8 Bucillamine has also been shown to avoid oxidative and reperfusion injury in heart and liver tissues8 and is extremely cell permeable for effective shipment into cells.8,9 Bucillamine has unrealized potential for the treatment of influenza with both proven safety and tested system of action similar to that of NAC, but with much higher effectiveness, reducing the previous barriers to utilizing thiols therapeutically. It is likewise sensible to hypothesize that comparable processes connected to ROS are involved in severe lung injury throughout nCov-19 infection, potentially justifying the investigation of bucillamine as an intervention for COVID-19.

Revive is establishing an item and scientific advancement strategy intending to unlock the complete capacity of Bucillamine. The Company will announce its initiatives as they unfold.

Current antiviral interventions for influenza have actually displayed modest efficacy, particularly in improving death in at-risk populations, such as the elderly.1,2 Novel antivirals have actually been pestered by poor oral bioavailability and lack of efficacy when not provided early.1 This is since these drugs mostly act to prevent the early processes of virus binding to cells or viral duplication.2 Thiols, especially N-acetylcysteine (NAC), with antioxidant and lowering activity have been examined as reliable treatments that abrogate the capacity for influenza to cause severe illness.3,4,5 Restoration of glutathione, the major intracellular thiol antioxidant, is a vital functional activity of NAC.6 Reactive oxygen types (ROS) generation during influenza virus infection worsen harmful inflammation and configured death of epithelial cells.7 Studies in human cells and animal designs have revealed that NAC works to prevent severe lung injury brought on by influenza virus infection through inhibition of these ROS-mediated systems.4,7 NAC has actually been examined scientifically and found to significantly attenuate medical signs connected with influenza infection, specifically in elderly at-risk patients.5 While NAC is quickly used up by cells and has low toxicity, scientific efficacy has actually required long-term and high-dose administration since of modest relative effectiveness, limiting its clinical applicability.

Revive is a company focused on the research, advancement and commercialization of unique psychedelic and cannabinoid-based life sciences products and drug repurposing for infectious illness. With its recent acquisition of Psilocin Pharma Corp., Revive will advance Psilocybin-based therapies in various diseases and disorders and will focus on advancement efforts to take benefit of several regulatory rewards awarded by the FDA such as Orphan Drug, Fast Track, Breakthrough Therapy and Rare Pediatric Disease classifications. The Company is likewise checking out the usage of Bucillamine for the potential treatment of infectious illness.

Referrals

1. Muthuri SG, Venkatesan S, Myles PR et al. Effectiveness of neuraminidase inhibitors in minimizing mortality in patients confessed to hospital with influenza A H1N1pdm09 virus infection: a meta-analysis of private participant data Lancet Respir Med. 2014 May; 2( 5 ):395 -404. doi: 10.1016/ S2213-2600( 14 )70041-4.

2. Duwe S. Influenza infections– antiviral therapy and resistance.

3. Zhang RH, Li CH, Wang CL et al. N-acetyl-l-cystine( NAC) secures versus H9N2 swine influenza virus-induced acute lung injury. Int Immunopharmacol. 2014 Sep; 22( 1 ):1 -8. doi: 10.1016/ j.intimp.2014.06.013.

Ungheri D, Pisani C, Sanson G et al. Protective impact of n-acetylcysteine in a model of influenza infection in mice.

5. De Flora S, Grassi C, and Carati L. Attenuation of influenza-like symptomatology and enhancement of cell-mediated immunity with long-term N-acetylcysteine treatment. Eur Respir J 1997; 10: 1535– 1541 DOI: 10.1183/ 09031936.97.10071535.

The Basics of Thiols and Cysteines in Redox Biology and Chemistry. Free Radic Biol Med. 2015 Mar; 0: 148– 157.

7. Mata M, Morcillo E, Gimeno C, Cortijo J. N-acetyl-L-cysteine (NAC) inhibit mucin synthesis and pro-inflammatory conciliators in alveolar type II epithelial cells contaminated with influenza infection A and B and with respiratory syncytial infection (RSV). Biochem Pharmacol. 2011 Sep 1; 82( 5 ):548 -55. doi: 10.1016/ j.bcp.2011.05.014.

Bucillamine: a potent thiol donor with several clinical applications. Cardiovasc Drug Rev. 2003 Summer; 21( 2 ):77 -90.

9. Sagawa A, Fujisaku A, Ohnishi K et al. A multicentre trial of bucillamine in the treatment of early rheumatoid arthritis (SNOW study). Mod Rheumatol. 2011 Jun; 21( 3 ):251 -7. doi: 10.1007/ s10165-010-0385-4.

Restore is a business focused on the research study, advancement and commercialization of novel psychedelic and cannabinoid-based life sciences items and drug repurposing for transmittable illness. Restores technology is being advanced to fill the medical needs for disorders and illness such as discomfort, inflammation, and injury care. Revives cannabinoid pharmaceutical portfolio focuses on unusual inflammatory locations such as liver illness. With its recent acquisition of Psilocin Pharma Corp., Revive will advance Psilocybin-based therapeutics in various diseases and conditions and will focus on development efforts to take advantage of several regulative incentives awarded by the FDA such as Orphan Drug, Fast Track, Breakthrough Therapy and Rare Pediatric Disease designations. The Company is also checking out the use of Bucillamine for the prospective treatment of infectious illness.

Advertisement:

Bestseller No. 1
Purge! Uric Acid Cleanse & Joint Support – Ready to Eat & Drink What You Want? – Active Mobility, Strong Flexibility, Healthy Inflammation – Tart Cherry & Celery Seed – 60 Vegetarian Soft Capsules
  • Joint comfort and detoxification promote healthy uric acid levels and maintain proper balance. You can have the confidence that every capsule has the strength and potency needed for uric acid support.
  • We blend all our products at a cGMP Certified Laboratory to ensure a contaminant-free product. We wouldn't have it any other way and neither should you.
  • Super ingredients rich in anthocyanins and antioxidants like Celery Seed and Tart Cherry Extract, Purge naturally promotes joint health, providing you with the best power to maintain comfort, flexibility, and mobility.
  • Pure natural formula in 100% vegetarian easy-to-swallow soft capsules, completely free of fillers, binders, and artificial ingredients. No gluten, wheat, or dairy. And of course, never tested on animals. Just a pure and tested product.
  • Try our products without worry with our 100% Happiness & Heath Commitment. We're confident that you will see results and be thrilled with your purchase. And through our Vitamin Angels 1-for-1 Match program, one bottle equals one year of vitamins for a child in need.
SaleBestseller No. 2
Uric Acid Cleanse with Tart Cherry 9600mg - Made in USA - Clinically Proven Natural Gоut Relief - Joint Comfort & Detoxification - Liquid Uric Acid Support Formula for High BioAvailability
  • Uric Acid Level Control - Concentrated Herbal Complex includes the right powerful mix of ingredients such as Tart Cherry & Celery Seed, which is clinically proven to support your healthy joints and uric acid balance in your system. This is the most efficient Uric Acid Level Control with 9600 mg Tart Cherry infused.
  • Max Absorption & Rapid Recovery - Our Uric Acid Cleanse with celery seed, as supporting ingredient, delivers potent anthocyanins to achieve joint comfort and recover muscles. The powerful combination provides joints with the ability to maintain comfort & flexibility naturally.
  • Strong Antioxidant Effect - The Unique Blend of Active Ingredients full of Vitamins & Trace Minerals, perfect for your health. Moreover, Polyphenols in Tart Cherry have more antioxidants than any other product. They protect your muscles from oxidative damage, support strength, and provide long-term wellness.
  • Pure Natural Formula - FairMile Organics is the most refined nutrition brand using zero fillers, binders, or artificial ingredients. We manufacture our product in the USA. Our tincture is gluten, wheat & dairy-free, and was never tested on animals.
  • Health Improvements & Satisfaction Guarantee - Be sure: you're fueling your body with the very best. We're confident that you will see results and be thrilled with your purchase. Otherwise, we are open to your proposals. Any of your questions will be resolved by professional customer service.
Bestseller No. 3
Uric Acid Support Supplement – Go-Out Tart Cherry Extract Capsules for SUSTAINED Relief, Improved Joint Health & Circulation with Celery Seed Extract, Turmeric, Bromelain by Mt. Angel Vitamins, 90-Ct.
  • LIVE LIVELY – Don’t let discomfort ruin your day. Ease joint pain and enjoy activities with Mt. Angel Vitamins! Go-Out uric acid cleanse provides sustained relief so you can get back on your feet!
  • IMPROVE & MOVE – Sick of stiffness? Help restore joint flexibility with black and tart cherry extract, celery seed extract, bromelain, and turmeric root. Go with go out capsules formulated with ingredients known to reduce inflammation.
  • GO WITH THE FLOW – By lowering uric acid levels, your go out relief capsules are known to fortify healthy circulation and blood pressure, protecting muscles and joints from damage.
  • SIMPLE SOLUTION – Enjoy a supplement that works with your schedule! To free yourself from pain, just take 1 of your 90 inflammation relief capsules twice daily. Support has never been so simple!
  • OUR PROMISE – At Mt. Angel Vitamins, we take pride in our capsules’ quality. We ensure your positive experience with restorative results from personally crafted and tested, non-GMO supplements!
Bestseller No. 4
Therapeutic Gout Relief Cream with Arnica Extract, Ilex Leaf Extract, Aloe Vera and Tea Tree Oil.
  • Immediate, Lasting & Quick Relief: Did you know that our unique pain relief cream is preferred by those dealing with inflammation, pain and discomfort related to flare-ups? Numerous All Natural pain relievers go to work to reduce inflammation, provide soothing relief and get you back on your feet!
  • Non-Greasy, Non-Staining & Fast Absorbing: Arnica gel cream with a refreshing mint scent. Within minutes, the cream is absorbed and the scent is vanished. Get back to your normal life!
  • Made In The USA: Manufactured and Packaged in the USA in a GMP Approved Facility for Purity and Potency
  • Natural Ingredients: Include Arnica Extract, Tea Tree Oil, Ilex Leaf Extract, Aloe, vitamins E & B6 and MSM.
  • Money Back Guarantee: We stand behind our Therapeutic Pain Relief Cream 100% and are sure you are going to love it! If you are less than 100% Satisfied with our product, for ANY reason, we will refund your money in full with no questions asked. What do you have to lose? Buy Now!
SaleBestseller No. 5
The Healing Gout Cookbook: Anti-Inflammatory Recipes to Lower Uric Acid Levels and Reduce Flares
  • Andrews MEd RD LD, Lisa Cicciarello (Author)
  • English (Publication Language)
  • 158 Pages - 03/31/2020 (Publication Date) - Rockridge Press (Publisher)
Bestseller No. 6
Urcinol - The Leading Uric Acid Supplement - 30 Day Supply. Premium Pain Relief & More Powerful Than Tart Cherry at Flushing Out Uric Acid.
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
Bestseller No. 7
NutriGout - Uric Acid Support Formula - 60 Vegetarian Capsules
  • Get Your Life Back - Sudden, severe pain caused by uric acid buildup strikes at the most unpredictable times. Take back control with NutriGout so you can do the things you love again
  • Stops Pain Before It Begins - Our uric acid supplement supports your kidneys and liver so that your body naturally flushes out excess uric acid before it gets out of control
  • All Natural Relief - Turmeric, Milk Thistle Extract, Bromelain, Celery Seed, Dandelion Extract and Chanca Piedra work synergistically, supporting normal, healthy UA levels
  • Made In The USA - Inspected in a GMP certified laboratory, our GMO-free formula contains no artificial colors or flavors. Powerful antioxidants can help restore joint flexibility, making it easier to rise out of bed in the morning and tackle your day
  • Need To Try It Before You Commit? We Guarantee your results, or your money back. So go ahead and click add to cart - your joints will thank you!
SaleBestseller No. 8
Uricel The Best Uric Acid Support Formula - High Potency Advanced Key Ingredients Designed to Support Healthy Uric Acid Levels with Tart Cherry, Celery Seed and More
  • TINGLE-FREE FEET & TOES. Uricel is a fast-acting herbal uric acid cleanse that helps balance uric acid levels to melt away the sharp tingling feeling in your feet and toes. By giving your body exactly what it needs to help expel the excess Uric acid which causes discomfort, the body can then do what it does best by helping return you get back to your normal self.
  • CLEANSE AND FLUSH URIC ACID and uric acid crystals that aggravate your feet, toes, and joints. Uricel is an herbal blend of Tart Cherry, Chanca Piedra, and Celery Seed that helps balance uric acid levels to target swelling and avoid future flare-ups. Our customers are constantly amazed by just how fast their discomfort in their feet, toes, and other affected joints melts away. Uricel is designed to help you regain your mobility and continue with your daily routines as quickly as possible.
  • SUPPORTS HEALTHY KIDNEYS, TOO. Purine content from diet and alcohol can form uric acid crystals that are difficult for your kidneys to pass. Chanca Piedrea translates to “stone breaker,” and Celery Seed is a mild diuretic that boosts urine flow to get uric acid moving out of the body and support healthy kidneys.
  • CAPSULES NEED TO BE DIGESTED, LIQUIDS DON’T. Have you ever seen a pill in nature? Neither have we, and frankly, we're tired of the nasty burps and eye-watering gulps. Liquids don't need to travel to your stomach before they start absorbing, liquids are immediately bioavailable and work fast! Not to mention, our alcohol-free tinctures taste great, and they're safe for kids, too.
  • CRAFTED UNDER THE GUIDANCE OF A TRAINED HERBALIST IN THE USA. Instead of cramming all these ingredients in a capsule that was thrown together somewhere in China, Uricel is made and manufactured in the USA. Each batch is 3rd-party tested for safety and purity so you only get the best.
Bestseller No. 9
Gout Complete 16oz - Natural & Organic Liquid Gout Treatment, Uric Acid Flush & Remedy Support Medicine (W/Tart Cherry)
  • WHY USE A LIQUID TREATMENT? – Research indicates that liquid supplements are more easily absorbed into the body. With an average absorption rate of better than 90% vs. pills at 10-15%, doesn’t it make sense that a liquid can control uric acid better and is the best alternative? Pills using the best of ingredients are simply less effective for relief.
  • PROVEN RESULTS – As a naturopathic remedy using only natural and organic ingredients, we addressed the root causes of uric acid buildup, kidney function and circulation. With proven ingredients that address kidney function, inflammation, pain, circulation, and many other health specific issues that take place to create the imbalance of uric acid in the body, these natural remedies are for you. Uric Acid Complete is used both during the course of an attack and as a preventative measure.
  • A COMPLETE ALTERNATIVE – With both Organic and Kosher certifications, we use only the highest concentration and quality of ingredients. We use more than 35 ingredients, 3 times more than any comparable product, to help reduce inflammation, increase circulation, cleanse and flush out infection, and rebalance Ph, mineral and uric acid levels. With our 100% SATISFACTION GUARANTEE, you can feel safe that you are making the best choice in a proven and natural uric acid reducer.
  • MADE IN THE USA! USDA Organic and OU Kosher Certified.
Bestseller No. 10
The 28-Day Gout Diet Plan: The Optimal Nutrition Guide to Manage Gout
  • Kamveris MS RD LDN, Sophia (Author)
  • English (Publication Language)
  • 194 Pages - 02/05/2019 (Publication Date) - Rockridge Press (Publisher)

I get commissions for purchases made through links on this website. As an Amazon Associate I earn from qualifying purchases.

Gout drug reduces adverse events in patients with hyperuricaemia

Clients were randomly assigned in a 1:1 ratio to get oral febuxostat for 36 months or not. In the febuxostat group, the dose was increased step-by-step from 10 to 40 mg daily if tolerated. In the non-febuxostat group, allopurinol 100 mg was thought about if serum uric acid was raised. In both groups, the dosage of febuxostat or allopurinol was changed to avoid a serum uric acid level less than 2 mg/dL. All patients were recommended to consume a healthy diet plan, gave up smoking, and exercise to help handle their hyperuricaemia.

Hyperuricaemia, an abnormally high serum uric acid level, causes gout and is associated with coronary artery illness, hypertension, stroke, kidney failure, and death. The FREED study2 analyzed whether decreasing uric acid with febuxostat avoids cerebral, cardiovascular and renal occasions and death in elderly patients with the condition.

Typical serum uric acid levels reached 4.4 mg/dL in the febuxostat group and 6.7 mg/dL in the group not receiving febuxostat.

Negative events were observed in 132 (24.6%) patients in the febuxostat group and 135 (25.3%) clients in the non-febuxostat group, without any substantial distinction in between the 2 groups (p= 0.83). 2 patients in the febuxostat group passed away. In the febuxostat group, mental condition, headache, high blood pressure, abdominal discomfort, diarrhoea, maculopapular rash, intense kidney injury, and oedema of the extremities happened in two clients each.

When the private elements of the main endpoint were evaluated independently, the most frequent occasion was renal problems, which happened in 16.2% of the febuxostat group and 20.5% of the non-febuxostat group. Amongst those with kidney disability, the development of microalbuminuria or moderate proteinuria was typical in both treatment groups.

Munich, Germany – 28 Aug 2018: Uric acid reduction with the gout treatment febuxostat decreases unfavorable events in senior patients with hyperuricaemia, according to late breaking research study presented today in a Hot Line Session at ESC Congress 2018.1

The primary endpoint happened in 125 (23%) clients in the febuxostat group and 153 (29%) clients in the non-febuxostat group. Febuxostat significantly minimized the rate of the main endpoint, with a threat ratio of 0.75 (95% self-confidence period 0.59-0.95, p= 0.017) (see figure).

Negative occasions were observed in 132 (24.6%) patients in the febuxostat group and 135 (25.3%) clients in the non-febuxostat group, with no substantial distinction between the two groups (p= 0.83). 2 clients in the febuxostat group died. In the febuxostat group, psychological disorder, headache, hypertension, abdominal pain, diarrhoea, maculopapular rash, acute kidney injury, and oedema of the extremities occurred in two patients each.

Professor Sunao Kojima, primary private investigator, Kawasaki Medical School, Okayama, Japan, stated:: “We found that patients receiving febuxostat were 25% less most likely to pass away or experience strokes, heart problem, or kidney illness over a three-year duration than clients who did not receive febuxostat. The findings recommend that lowering uric acid with febuxostat provides scientific benefit.”.

The research study enrolled 1,070 patients aged 65 years and older with hyperuricaemia (serum uric acid 7-9 mg/dL) and at threat for cerebral, cardiovascular, or renal events as defined by the existence of high blood pressure, type 2 diabetes, kidney disorder, or a history of cerebral or cardiovascular disease.3.

A total of 537 patients received febuxostat and the average dosage at the end of the study was 29 mg. Of the 533 patients in the non-febuxostat group, 27% got allopurinol 100 mg. Average serum uric acid levels reached 4.4 mg/dL in the febuxostat group and 6.7 mg/dL in the group not getting febuxostat.

Patients were followed-up for 36 months for the main endpoint which was a composite of cerebral, cardiovascular, and renal occasions, and death from any cause. This included death due to cerebral or cardiorenal vascular illness, brand-new or repeating cerebrovascular disease, brand-new or recurring coronary artery disease, cardiac failure needing hospitalisation, arteriosclerotic disease requiring treatment, renal illness (development of microalbuminuria, progression to overt proteinuria, or intensifying of obvious proteinuria to? 300 mg/g albumin/creatinine, doubling of serum creatinine level, progression to end phase kidney disease specified as estimated glomerular purification rate << 15 mL/min/1.73 m2), and new atrial fibrillation.

Advertisement:

Bestseller No. 1
Purge! Uric Acid Cleanse & Joint Support – Ready to Eat & Drink What You Want? – Active Mobility, Strong Flexibility, Healthy Inflammation – Tart Cherry & Celery Seed – 60 Vegetarian Soft Capsules
  • Joint comfort and detoxification promote healthy uric acid levels and maintain proper balance. You can have the confidence that every capsule has the strength and potency needed for uric acid support.
  • We blend all our products at a cGMP Certified Laboratory to ensure a contaminant-free product. We wouldn't have it any other way and neither should you.
  • Super ingredients rich in anthocyanins and antioxidants like Celery Seed and Tart Cherry Extract, Purge naturally promotes joint health, providing you with the best power to maintain comfort, flexibility, and mobility.
  • Pure natural formula in 100% vegetarian easy-to-swallow soft capsules, completely free of fillers, binders, and artificial ingredients. No gluten, wheat, or dairy. And of course, never tested on animals. Just a pure and tested product.
  • Try our products without worry with our 100% Happiness & Heath Commitment. We're confident that you will see results and be thrilled with your purchase. And through our Vitamin Angels 1-for-1 Match program, one bottle equals one year of vitamins for a child in need.
SaleBestseller No. 2
Uric Acid Cleanse with Tart Cherry 9600mg - Made in USA - Clinically Proven Natural Gоut Relief - Joint Comfort & Detoxification - Liquid Uric Acid Support Formula for High BioAvailability
  • Uric Acid Level Control - Concentrated Herbal Complex includes the right powerful mix of ingredients such as Tart Cherry & Celery Seed, which is clinically proven to support your healthy joints and uric acid balance in your system. This is the most efficient Uric Acid Level Control with 9600 mg Tart Cherry infused.
  • Max Absorption & Rapid Recovery - Our Uric Acid Cleanse with celery seed, as supporting ingredient, delivers potent anthocyanins to achieve joint comfort and recover muscles. The powerful combination provides joints with the ability to maintain comfort & flexibility naturally.
  • Strong Antioxidant Effect - The Unique Blend of Active Ingredients full of Vitamins & Trace Minerals, perfect for your health. Moreover, Polyphenols in Tart Cherry have more antioxidants than any other product. They protect your muscles from oxidative damage, support strength, and provide long-term wellness.
  • Pure Natural Formula - FairMile Organics is the most refined nutrition brand using zero fillers, binders, or artificial ingredients. We manufacture our product in the USA. Our tincture is gluten, wheat & dairy-free, and was never tested on animals.
  • Health Improvements & Satisfaction Guarantee - Be sure: you're fueling your body with the very best. We're confident that you will see results and be thrilled with your purchase. Otherwise, we are open to your proposals. Any of your questions will be resolved by professional customer service.
Bestseller No. 3
Uric Acid Support Supplement – Go-Out Tart Cherry Extract Capsules for SUSTAINED Relief, Improved Joint Health & Circulation with Celery Seed Extract, Turmeric, Bromelain by Mt. Angel Vitamins, 90-Ct.
  • LIVE LIVELY – Don’t let discomfort ruin your day. Ease joint pain and enjoy activities with Mt. Angel Vitamins! Go-Out uric acid cleanse provides sustained relief so you can get back on your feet!
  • IMPROVE & MOVE – Sick of stiffness? Help restore joint flexibility with black and tart cherry extract, celery seed extract, bromelain, and turmeric root. Go with go out capsules formulated with ingredients known to reduce inflammation.
  • GO WITH THE FLOW – By lowering uric acid levels, your go out relief capsules are known to fortify healthy circulation and blood pressure, protecting muscles and joints from damage.
  • SIMPLE SOLUTION – Enjoy a supplement that works with your schedule! To free yourself from pain, just take 1 of your 90 inflammation relief capsules twice daily. Support has never been so simple!
  • OUR PROMISE – At Mt. Angel Vitamins, we take pride in our capsules’ quality. We ensure your positive experience with restorative results from personally crafted and tested, non-GMO supplements!
Bestseller No. 4
Therapeutic Gout Relief Cream with Arnica Extract, Ilex Leaf Extract, Aloe Vera and Tea Tree Oil.
  • Immediate, Lasting & Quick Relief: Did you know that our unique pain relief cream is preferred by those dealing with inflammation, pain and discomfort related to flare-ups? Numerous All Natural pain relievers go to work to reduce inflammation, provide soothing relief and get you back on your feet!
  • Non-Greasy, Non-Staining & Fast Absorbing: Arnica gel cream with a refreshing mint scent. Within minutes, the cream is absorbed and the scent is vanished. Get back to your normal life!
  • Made In The USA: Manufactured and Packaged in the USA in a GMP Approved Facility for Purity and Potency
  • Natural Ingredients: Include Arnica Extract, Tea Tree Oil, Ilex Leaf Extract, Aloe, vitamins E & B6 and MSM.
  • Money Back Guarantee: We stand behind our Therapeutic Pain Relief Cream 100% and are sure you are going to love it! If you are less than 100% Satisfied with our product, for ANY reason, we will refund your money in full with no questions asked. What do you have to lose? Buy Now!
SaleBestseller No. 5
The Healing Gout Cookbook: Anti-Inflammatory Recipes to Lower Uric Acid Levels and Reduce Flares
  • Andrews MEd RD LD, Lisa Cicciarello (Author)
  • English (Publication Language)
  • 158 Pages - 03/31/2020 (Publication Date) - Rockridge Press (Publisher)
Bestseller No. 6
Urcinol - The Leading Uric Acid Supplement - 30 Day Supply. Premium Pain Relief & More Powerful Than Tart Cherry at Flushing Out Uric Acid.
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
Bestseller No. 7
NutriGout - Uric Acid Support Formula - 60 Vegetarian Capsules
  • Get Your Life Back - Sudden, severe pain caused by uric acid buildup strikes at the most unpredictable times. Take back control with NutriGout so you can do the things you love again
  • Stops Pain Before It Begins - Our uric acid supplement supports your kidneys and liver so that your body naturally flushes out excess uric acid before it gets out of control
  • All Natural Relief - Turmeric, Milk Thistle Extract, Bromelain, Celery Seed, Dandelion Extract and Chanca Piedra work synergistically, supporting normal, healthy UA levels
  • Made In The USA - Inspected in a GMP certified laboratory, our GMO-free formula contains no artificial colors or flavors. Powerful antioxidants can help restore joint flexibility, making it easier to rise out of bed in the morning and tackle your day
  • Need To Try It Before You Commit? We Guarantee your results, or your money back. So go ahead and click add to cart - your joints will thank you!
SaleBestseller No. 8
Uricel The Best Uric Acid Support Formula - High Potency Advanced Key Ingredients Designed to Support Healthy Uric Acid Levels with Tart Cherry, Celery Seed and More
  • TINGLE-FREE FEET & TOES. Uricel is a fast-acting herbal uric acid cleanse that helps balance uric acid levels to melt away the sharp tingling feeling in your feet and toes. By giving your body exactly what it needs to help expel the excess Uric acid which causes discomfort, the body can then do what it does best by helping return you get back to your normal self.
  • CLEANSE AND FLUSH URIC ACID and uric acid crystals that aggravate your feet, toes, and joints. Uricel is an herbal blend of Tart Cherry, Chanca Piedra, and Celery Seed that helps balance uric acid levels to target swelling and avoid future flare-ups. Our customers are constantly amazed by just how fast their discomfort in their feet, toes, and other affected joints melts away. Uricel is designed to help you regain your mobility and continue with your daily routines as quickly as possible.
  • SUPPORTS HEALTHY KIDNEYS, TOO. Purine content from diet and alcohol can form uric acid crystals that are difficult for your kidneys to pass. Chanca Piedrea translates to “stone breaker,” and Celery Seed is a mild diuretic that boosts urine flow to get uric acid moving out of the body and support healthy kidneys.
  • CAPSULES NEED TO BE DIGESTED, LIQUIDS DON’T. Have you ever seen a pill in nature? Neither have we, and frankly, we're tired of the nasty burps and eye-watering gulps. Liquids don't need to travel to your stomach before they start absorbing, liquids are immediately bioavailable and work fast! Not to mention, our alcohol-free tinctures taste great, and they're safe for kids, too.
  • CRAFTED UNDER THE GUIDANCE OF A TRAINED HERBALIST IN THE USA. Instead of cramming all these ingredients in a capsule that was thrown together somewhere in China, Uricel is made and manufactured in the USA. Each batch is 3rd-party tested for safety and purity so you only get the best.
Bestseller No. 9
Gout Complete 16oz - Natural & Organic Liquid Gout Treatment, Uric Acid Flush & Remedy Support Medicine (W/Tart Cherry)
  • WHY USE A LIQUID TREATMENT? – Research indicates that liquid supplements are more easily absorbed into the body. With an average absorption rate of better than 90% vs. pills at 10-15%, doesn’t it make sense that a liquid can control uric acid better and is the best alternative? Pills using the best of ingredients are simply less effective for relief.
  • PROVEN RESULTS – As a naturopathic remedy using only natural and organic ingredients, we addressed the root causes of uric acid buildup, kidney function and circulation. With proven ingredients that address kidney function, inflammation, pain, circulation, and many other health specific issues that take place to create the imbalance of uric acid in the body, these natural remedies are for you. Uric Acid Complete is used both during the course of an attack and as a preventative measure.
  • A COMPLETE ALTERNATIVE – With both Organic and Kosher certifications, we use only the highest concentration and quality of ingredients. We use more than 35 ingredients, 3 times more than any comparable product, to help reduce inflammation, increase circulation, cleanse and flush out infection, and rebalance Ph, mineral and uric acid levels. With our 100% SATISFACTION GUARANTEE, you can feel safe that you are making the best choice in a proven and natural uric acid reducer.
  • MADE IN THE USA! USDA Organic and OU Kosher Certified.
Bestseller No. 10
The 28-Day Gout Diet Plan: The Optimal Nutrition Guide to Manage Gout
  • Kamveris MS RD LDN, Sophia (Author)
  • English (Publication Language)
  • 194 Pages - 02/05/2019 (Publication Date) - Rockridge Press (Publisher)

I get commissions for purchases made through links on this website. As an Amazon Associate I earn from qualifying purchases.

Optimal gout treatment requires ongoing monitoring for urate lowering therapy

Managing gout as a chronic, instead of an acute, condition could assist avoid reoccurrences. A brand-new research study of more than 8,000 medical records discovered a positive association in between starting treatment with allopurinol, a medication that helps prevent gout by decreasing production of uric acid, and recurring medical professional gos to for the condition. Clinicians may therefore be most likely to offer allopurinol, or clients might be more most likely to accept it, after several severe gout attacks. Particularly, while patients eligible for allopurinol at standard were most likely to receive it than ineligible patients, time-varying covariates suggest a modification in the strength of the association with each extra system of time; for every single additional month of follow up, the threat ratio for allopurinol initiation in men increased by 0.007 (0.004-0.01). The authors suggest that more frequent persistent illness evaluates to examine clients choices and eligibility for allopurinol might decrease barriers to effectively dealing with gout.

Advertisement:

Bestseller No. 1
Purge! Uric Acid Cleanse & Joint Support – Ready to Eat & Drink What You Want? – Active Mobility, Strong Flexibility, Healthy Inflammation – Tart Cherry & Celery Seed – 60 Vegetarian Soft Capsules
  • Joint comfort and detoxification promote healthy uric acid levels and maintain proper balance. You can have the confidence that every capsule has the strength and potency needed for uric acid support.
  • We blend all our products at a cGMP Certified Laboratory to ensure a contaminant-free product. We wouldn't have it any other way and neither should you.
  • Super ingredients rich in anthocyanins and antioxidants like Celery Seed and Tart Cherry Extract, Purge naturally promotes joint health, providing you with the best power to maintain comfort, flexibility, and mobility.
  • Pure natural formula in 100% vegetarian easy-to-swallow soft capsules, completely free of fillers, binders, and artificial ingredients. No gluten, wheat, or dairy. And of course, never tested on animals. Just a pure and tested product.
  • Try our products without worry with our 100% Happiness & Heath Commitment. We're confident that you will see results and be thrilled with your purchase. And through our Vitamin Angels 1-for-1 Match program, one bottle equals one year of vitamins for a child in need.
SaleBestseller No. 2
Uric Acid Cleanse with Tart Cherry 9600mg - Made in USA - Clinically Proven Natural Gоut Relief - Joint Comfort & Detoxification - Liquid Uric Acid Support Formula for High BioAvailability
  • Uric Acid Level Control - Concentrated Herbal Complex includes the right powerful mix of ingredients such as Tart Cherry & Celery Seed, which is clinically proven to support your healthy joints and uric acid balance in your system. This is the most efficient Uric Acid Level Control with 9600 mg Tart Cherry infused.
  • Max Absorption & Rapid Recovery - Our Uric Acid Cleanse with celery seed, as supporting ingredient, delivers potent anthocyanins to achieve joint comfort and recover muscles. The powerful combination provides joints with the ability to maintain comfort & flexibility naturally.
  • Strong Antioxidant Effect - The Unique Blend of Active Ingredients full of Vitamins & Trace Minerals, perfect for your health. Moreover, Polyphenols in Tart Cherry have more antioxidants than any other product. They protect your muscles from oxidative damage, support strength, and provide long-term wellness.
  • Pure Natural Formula - FairMile Organics is the most refined nutrition brand using zero fillers, binders, or artificial ingredients. We manufacture our product in the USA. Our tincture is gluten, wheat & dairy-free, and was never tested on animals.
  • Health Improvements & Satisfaction Guarantee - Be sure: you're fueling your body with the very best. We're confident that you will see results and be thrilled with your purchase. Otherwise, we are open to your proposals. Any of your questions will be resolved by professional customer service.
Bestseller No. 3
Uric Acid Support Supplement – Go-Out Tart Cherry Extract Capsules for SUSTAINED Relief, Improved Joint Health & Circulation with Celery Seed Extract, Turmeric, Bromelain by Mt. Angel Vitamins, 90-Ct.
  • LIVE LIVELY – Don’t let discomfort ruin your day. Ease joint pain and enjoy activities with Mt. Angel Vitamins! Go-Out uric acid cleanse provides sustained relief so you can get back on your feet!
  • IMPROVE & MOVE – Sick of stiffness? Help restore joint flexibility with black and tart cherry extract, celery seed extract, bromelain, and turmeric root. Go with go out capsules formulated with ingredients known to reduce inflammation.
  • GO WITH THE FLOW – By lowering uric acid levels, your go out relief capsules are known to fortify healthy circulation and blood pressure, protecting muscles and joints from damage.
  • SIMPLE SOLUTION – Enjoy a supplement that works with your schedule! To free yourself from pain, just take 1 of your 90 inflammation relief capsules twice daily. Support has never been so simple!
  • OUR PROMISE – At Mt. Angel Vitamins, we take pride in our capsules’ quality. We ensure your positive experience with restorative results from personally crafted and tested, non-GMO supplements!
Bestseller No. 4
Therapeutic Gout Relief Cream with Arnica Extract, Ilex Leaf Extract, Aloe Vera and Tea Tree Oil.
  • Immediate, Lasting & Quick Relief: Did you know that our unique pain relief cream is preferred by those dealing with inflammation, pain and discomfort related to flare-ups? Numerous All Natural pain relievers go to work to reduce inflammation, provide soothing relief and get you back on your feet!
  • Non-Greasy, Non-Staining & Fast Absorbing: Arnica gel cream with a refreshing mint scent. Within minutes, the cream is absorbed and the scent is vanished. Get back to your normal life!
  • Made In The USA: Manufactured and Packaged in the USA in a GMP Approved Facility for Purity and Potency
  • Natural Ingredients: Include Arnica Extract, Tea Tree Oil, Ilex Leaf Extract, Aloe, vitamins E & B6 and MSM.
  • Money Back Guarantee: We stand behind our Therapeutic Pain Relief Cream 100% and are sure you are going to love it! If you are less than 100% Satisfied with our product, for ANY reason, we will refund your money in full with no questions asked. What do you have to lose? Buy Now!
SaleBestseller No. 5
The Healing Gout Cookbook: Anti-Inflammatory Recipes to Lower Uric Acid Levels and Reduce Flares
  • Andrews MEd RD LD, Lisa Cicciarello (Author)
  • English (Publication Language)
  • 158 Pages - 03/31/2020 (Publication Date) - Rockridge Press (Publisher)
Bestseller No. 6
Urcinol - The Leading Uric Acid Supplement - 30 Day Supply. Premium Pain Relief & More Powerful Than Tart Cherry at Flushing Out Uric Acid.
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
Bestseller No. 7
NutriGout - Uric Acid Support Formula - 60 Vegetarian Capsules
  • Get Your Life Back - Sudden, severe pain caused by uric acid buildup strikes at the most unpredictable times. Take back control with NutriGout so you can do the things you love again
  • Stops Pain Before It Begins - Our uric acid supplement supports your kidneys and liver so that your body naturally flushes out excess uric acid before it gets out of control
  • All Natural Relief - Turmeric, Milk Thistle Extract, Bromelain, Celery Seed, Dandelion Extract and Chanca Piedra work synergistically, supporting normal, healthy UA levels
  • Made In The USA - Inspected in a GMP certified laboratory, our GMO-free formula contains no artificial colors or flavors. Powerful antioxidants can help restore joint flexibility, making it easier to rise out of bed in the morning and tackle your day
  • Need To Try It Before You Commit? We Guarantee your results, or your money back. So go ahead and click add to cart - your joints will thank you!
SaleBestseller No. 8
Uricel The Best Uric Acid Support Formula - High Potency Advanced Key Ingredients Designed to Support Healthy Uric Acid Levels with Tart Cherry, Celery Seed and More
  • TINGLE-FREE FEET & TOES. Uricel is a fast-acting herbal uric acid cleanse that helps balance uric acid levels to melt away the sharp tingling feeling in your feet and toes. By giving your body exactly what it needs to help expel the excess Uric acid which causes discomfort, the body can then do what it does best by helping return you get back to your normal self.
  • CLEANSE AND FLUSH URIC ACID and uric acid crystals that aggravate your feet, toes, and joints. Uricel is an herbal blend of Tart Cherry, Chanca Piedra, and Celery Seed that helps balance uric acid levels to target swelling and avoid future flare-ups. Our customers are constantly amazed by just how fast their discomfort in their feet, toes, and other affected joints melts away. Uricel is designed to help you regain your mobility and continue with your daily routines as quickly as possible.
  • SUPPORTS HEALTHY KIDNEYS, TOO. Purine content from diet and alcohol can form uric acid crystals that are difficult for your kidneys to pass. Chanca Piedrea translates to “stone breaker,” and Celery Seed is a mild diuretic that boosts urine flow to get uric acid moving out of the body and support healthy kidneys.
  • CAPSULES NEED TO BE DIGESTED, LIQUIDS DON’T. Have you ever seen a pill in nature? Neither have we, and frankly, we're tired of the nasty burps and eye-watering gulps. Liquids don't need to travel to your stomach before they start absorbing, liquids are immediately bioavailable and work fast! Not to mention, our alcohol-free tinctures taste great, and they're safe for kids, too.
  • CRAFTED UNDER THE GUIDANCE OF A TRAINED HERBALIST IN THE USA. Instead of cramming all these ingredients in a capsule that was thrown together somewhere in China, Uricel is made and manufactured in the USA. Each batch is 3rd-party tested for safety and purity so you only get the best.
Bestseller No. 9
Gout Complete 16oz - Natural & Organic Liquid Gout Treatment, Uric Acid Flush & Remedy Support Medicine (W/Tart Cherry)
  • WHY USE A LIQUID TREATMENT? – Research indicates that liquid supplements are more easily absorbed into the body. With an average absorption rate of better than 90% vs. pills at 10-15%, doesn’t it make sense that a liquid can control uric acid better and is the best alternative? Pills using the best of ingredients are simply less effective for relief.
  • PROVEN RESULTS – As a naturopathic remedy using only natural and organic ingredients, we addressed the root causes of uric acid buildup, kidney function and circulation. With proven ingredients that address kidney function, inflammation, pain, circulation, and many other health specific issues that take place to create the imbalance of uric acid in the body, these natural remedies are for you. Uric Acid Complete is used both during the course of an attack and as a preventative measure.
  • A COMPLETE ALTERNATIVE – With both Organic and Kosher certifications, we use only the highest concentration and quality of ingredients. We use more than 35 ingredients, 3 times more than any comparable product, to help reduce inflammation, increase circulation, cleanse and flush out infection, and rebalance Ph, mineral and uric acid levels. With our 100% SATISFACTION GUARANTEE, you can feel safe that you are making the best choice in a proven and natural uric acid reducer.
  • MADE IN THE USA! USDA Organic and OU Kosher Certified.
Bestseller No. 10
The 28-Day Gout Diet Plan: The Optimal Nutrition Guide to Manage Gout
  • Kamveris MS RD LDN, Sophia (Author)
  • English (Publication Language)
  • 194 Pages - 02/05/2019 (Publication Date) - Rockridge Press (Publisher)

I get commissions for purchases made through links on this website. As an Amazon Associate I earn from qualifying purchases.

Drug used to slow kidney disease found to be ineffective

“Based on our study results, it appears that raised blood urate levels are more than likely a sign of lowered kidney function rather than a cause of lowered kidney function,” said A/Prof Badve.

” We felt it was very important to collect proof of allopurinols effect on clients with kidney illness who have actually never had gout,” stated Professor Johnson.

Around 1.7 million Australians and 400,000 New Zealanders aged 18 years and over have chronic kidney disease.

They found the drug is inadequate in dealing with the condition, in spite of as much as 20 per cent of kidney disease clients being prescribed the medication.

The George Institute for Global Health Senior Research Fellow and St George Hospital nephrologist, Associate Professor Sunil Badve said the commonly held view that elevated blood urate levels was accountable for fast decline of kidney function was most likely wrong.

The CKD-FIX study stumbled upon 31 healthcare facilities in Australia and New Zealand, with more than 369 patients -with stage 3 or 4 chronic kidney illness who were at increased threat of further progression – participating in the trial.

” In the CKD-FIX study, we compared the usage of allopurinol to a placebo and discovered, to our surprise, that it made no difference to the rate of kidney function decrease,” he said.

“Trials which show existing treatments to be not as effective as prepared for, enable those medications to be stopped or not started in the very first place, lowering unnecessary healthcare costs,” said Dr de Zoysa.

The Australasian Kidney Trials Network led a big, two-year research study, called CKD-FIX, to examine the effectiveness of allopurinol, in slowing the rate of decline in kidney function.

Lead Investigator-New Zealand, Dr Janak de Zoysa from the University of Auckland and Waitemata District Health Board said trials like CKD-FIX were extremely crucial as they enabled doctors to optimise clinical practice.

Following a significant clinical trial, clinicians discover the drug allopurinol does not avoid getting worse of kidney illness.

” Based on these results our company believe there is no benefit in prescribing this medication, unless there is an extra particular medical reason, such as gout. This much awaited, high-quality proof will notify worldwide medical standards for patient treatment.

In the paper, the study authors reported a 35% reduction in blood urate levels, which was kept throughout the two-year study period for clients prescribed allopurinol. Kidney function, however, declined at similar rates for two treatment groups; allopurinol -3.33 mL/min/1.73 m2/year (95% CI -4 · 11 to -2 · 55) and control -3.23 mL/min/1.73 m2/year (95% CI -3 · 98 to -2 · 47). There was no difference in the amount of protein in the urine and high blood pressure in between the groups.

Queensland Renal Transplant Service Medical Director and University of Queensland Professor of Medicine based at the Translational Research Institute, David Johnson, stated up until now there had actually been little robust evidence to show allopurinols benefit in slowing the rate of decline in kidney function.

The arise from the research study were published in The New England Journal of Medicine.

Commercially available since the late 1960s, allopurinol helps the body decrease urate in the blood. High levels of the chemical prevail amongst clients with chronic kidney illness, where it is related to a greater risk of establishing persistent kidney disease and its progression.

” It is very important, however, that individuals with kidney illness who are already taking a medication like allopurinol to lower blood urate levels dont abruptly stop this treatment. They must discuss their kidney care management with their physician first.”

Advertisement:

Bestseller No. 1
Purge! Uric Acid Cleanse & Joint Support – Ready to Eat & Drink What You Want? – Active Mobility, Strong Flexibility, Healthy Inflammation – Tart Cherry & Celery Seed – 60 Vegetarian Soft Capsules
  • Joint comfort and detoxification promote healthy uric acid levels and maintain proper balance. You can have the confidence that every capsule has the strength and potency needed for uric acid support.
  • We blend all our products at a cGMP Certified Laboratory to ensure a contaminant-free product. We wouldn't have it any other way and neither should you.
  • Super ingredients rich in anthocyanins and antioxidants like Celery Seed and Tart Cherry Extract, Purge naturally promotes joint health, providing you with the best power to maintain comfort, flexibility, and mobility.
  • Pure natural formula in 100% vegetarian easy-to-swallow soft capsules, completely free of fillers, binders, and artificial ingredients. No gluten, wheat, or dairy. And of course, never tested on animals. Just a pure and tested product.
  • Try our products without worry with our 100% Happiness & Heath Commitment. We're confident that you will see results and be thrilled with your purchase. And through our Vitamin Angels 1-for-1 Match program, one bottle equals one year of vitamins for a child in need.
SaleBestseller No. 2
Uric Acid Cleanse with Tart Cherry 9600mg - Made in USA - Clinically Proven Natural Gоut Relief - Joint Comfort & Detoxification - Liquid Uric Acid Support Formula for High BioAvailability
  • Uric Acid Level Control - Concentrated Herbal Complex includes the right powerful mix of ingredients such as Tart Cherry & Celery Seed, which is clinically proven to support your healthy joints and uric acid balance in your system. This is the most efficient Uric Acid Level Control with 9600 mg Tart Cherry infused.
  • Max Absorption & Rapid Recovery - Our Uric Acid Cleanse with celery seed, as supporting ingredient, delivers potent anthocyanins to achieve joint comfort and recover muscles. The powerful combination provides joints with the ability to maintain comfort & flexibility naturally.
  • Strong Antioxidant Effect - The Unique Blend of Active Ingredients full of Vitamins & Trace Minerals, perfect for your health. Moreover, Polyphenols in Tart Cherry have more antioxidants than any other product. They protect your muscles from oxidative damage, support strength, and provide long-term wellness.
  • Pure Natural Formula - FairMile Organics is the most refined nutrition brand using zero fillers, binders, or artificial ingredients. We manufacture our product in the USA. Our tincture is gluten, wheat & dairy-free, and was never tested on animals.
  • Health Improvements & Satisfaction Guarantee - Be sure: you're fueling your body with the very best. We're confident that you will see results and be thrilled with your purchase. Otherwise, we are open to your proposals. Any of your questions will be resolved by professional customer service.
Bestseller No. 3
Uric Acid Support Supplement – Go-Out Tart Cherry Extract Capsules for SUSTAINED Relief, Improved Joint Health & Circulation with Celery Seed Extract, Turmeric, Bromelain by Mt. Angel Vitamins, 90-Ct.
  • LIVE LIVELY – Don’t let discomfort ruin your day. Ease joint pain and enjoy activities with Mt. Angel Vitamins! Go-Out uric acid cleanse provides sustained relief so you can get back on your feet!
  • IMPROVE & MOVE – Sick of stiffness? Help restore joint flexibility with black and tart cherry extract, celery seed extract, bromelain, and turmeric root. Go with go out capsules formulated with ingredients known to reduce inflammation.
  • GO WITH THE FLOW – By lowering uric acid levels, your go out relief capsules are known to fortify healthy circulation and blood pressure, protecting muscles and joints from damage.
  • SIMPLE SOLUTION – Enjoy a supplement that works with your schedule! To free yourself from pain, just take 1 of your 90 inflammation relief capsules twice daily. Support has never been so simple!
  • OUR PROMISE – At Mt. Angel Vitamins, we take pride in our capsules’ quality. We ensure your positive experience with restorative results from personally crafted and tested, non-GMO supplements!
Bestseller No. 4
Therapeutic Gout Relief Cream with Arnica Extract, Ilex Leaf Extract, Aloe Vera and Tea Tree Oil.
  • Immediate, Lasting & Quick Relief: Did you know that our unique pain relief cream is preferred by those dealing with inflammation, pain and discomfort related to flare-ups? Numerous All Natural pain relievers go to work to reduce inflammation, provide soothing relief and get you back on your feet!
  • Non-Greasy, Non-Staining & Fast Absorbing: Arnica gel cream with a refreshing mint scent. Within minutes, the cream is absorbed and the scent is vanished. Get back to your normal life!
  • Made In The USA: Manufactured and Packaged in the USA in a GMP Approved Facility for Purity and Potency
  • Natural Ingredients: Include Arnica Extract, Tea Tree Oil, Ilex Leaf Extract, Aloe, vitamins E & B6 and MSM.
  • Money Back Guarantee: We stand behind our Therapeutic Pain Relief Cream 100% and are sure you are going to love it! If you are less than 100% Satisfied with our product, for ANY reason, we will refund your money in full with no questions asked. What do you have to lose? Buy Now!
SaleBestseller No. 5
The Healing Gout Cookbook: Anti-Inflammatory Recipes to Lower Uric Acid Levels and Reduce Flares
  • Andrews MEd RD LD, Lisa Cicciarello (Author)
  • English (Publication Language)
  • 158 Pages - 03/31/2020 (Publication Date) - Rockridge Press (Publisher)
Bestseller No. 6
Urcinol - The Leading Uric Acid Supplement - 30 Day Supply. Premium Pain Relief & More Powerful Than Tart Cherry at Flushing Out Uric Acid.
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
Bestseller No. 7
NutriGout - Uric Acid Support Formula - 60 Vegetarian Capsules
  • Get Your Life Back - Sudden, severe pain caused by uric acid buildup strikes at the most unpredictable times. Take back control with NutriGout so you can do the things you love again
  • Stops Pain Before It Begins - Our uric acid supplement supports your kidneys and liver so that your body naturally flushes out excess uric acid before it gets out of control
  • All Natural Relief - Turmeric, Milk Thistle Extract, Bromelain, Celery Seed, Dandelion Extract and Chanca Piedra work synergistically, supporting normal, healthy UA levels
  • Made In The USA - Inspected in a GMP certified laboratory, our GMO-free formula contains no artificial colors or flavors. Powerful antioxidants can help restore joint flexibility, making it easier to rise out of bed in the morning and tackle your day
  • Need To Try It Before You Commit? We Guarantee your results, or your money back. So go ahead and click add to cart - your joints will thank you!
SaleBestseller No. 8
Uricel The Best Uric Acid Support Formula - High Potency Advanced Key Ingredients Designed to Support Healthy Uric Acid Levels with Tart Cherry, Celery Seed and More
  • TINGLE-FREE FEET & TOES. Uricel is a fast-acting herbal uric acid cleanse that helps balance uric acid levels to melt away the sharp tingling feeling in your feet and toes. By giving your body exactly what it needs to help expel the excess Uric acid which causes discomfort, the body can then do what it does best by helping return you get back to your normal self.
  • CLEANSE AND FLUSH URIC ACID and uric acid crystals that aggravate your feet, toes, and joints. Uricel is an herbal blend of Tart Cherry, Chanca Piedra, and Celery Seed that helps balance uric acid levels to target swelling and avoid future flare-ups. Our customers are constantly amazed by just how fast their discomfort in their feet, toes, and other affected joints melts away. Uricel is designed to help you regain your mobility and continue with your daily routines as quickly as possible.
  • SUPPORTS HEALTHY KIDNEYS, TOO. Purine content from diet and alcohol can form uric acid crystals that are difficult for your kidneys to pass. Chanca Piedrea translates to “stone breaker,” and Celery Seed is a mild diuretic that boosts urine flow to get uric acid moving out of the body and support healthy kidneys.
  • CAPSULES NEED TO BE DIGESTED, LIQUIDS DON’T. Have you ever seen a pill in nature? Neither have we, and frankly, we're tired of the nasty burps and eye-watering gulps. Liquids don't need to travel to your stomach before they start absorbing, liquids are immediately bioavailable and work fast! Not to mention, our alcohol-free tinctures taste great, and they're safe for kids, too.
  • CRAFTED UNDER THE GUIDANCE OF A TRAINED HERBALIST IN THE USA. Instead of cramming all these ingredients in a capsule that was thrown together somewhere in China, Uricel is made and manufactured in the USA. Each batch is 3rd-party tested for safety and purity so you only get the best.
Bestseller No. 9
Gout Complete 16oz - Natural & Organic Liquid Gout Treatment, Uric Acid Flush & Remedy Support Medicine (W/Tart Cherry)
  • WHY USE A LIQUID TREATMENT? – Research indicates that liquid supplements are more easily absorbed into the body. With an average absorption rate of better than 90% vs. pills at 10-15%, doesn’t it make sense that a liquid can control uric acid better and is the best alternative? Pills using the best of ingredients are simply less effective for relief.
  • PROVEN RESULTS – As a naturopathic remedy using only natural and organic ingredients, we addressed the root causes of uric acid buildup, kidney function and circulation. With proven ingredients that address kidney function, inflammation, pain, circulation, and many other health specific issues that take place to create the imbalance of uric acid in the body, these natural remedies are for you. Uric Acid Complete is used both during the course of an attack and as a preventative measure.
  • A COMPLETE ALTERNATIVE – With both Organic and Kosher certifications, we use only the highest concentration and quality of ingredients. We use more than 35 ingredients, 3 times more than any comparable product, to help reduce inflammation, increase circulation, cleanse and flush out infection, and rebalance Ph, mineral and uric acid levels. With our 100% SATISFACTION GUARANTEE, you can feel safe that you are making the best choice in a proven and natural uric acid reducer.
  • MADE IN THE USA! USDA Organic and OU Kosher Certified.
Bestseller No. 10
The 28-Day Gout Diet Plan: The Optimal Nutrition Guide to Manage Gout
  • Kamveris MS RD LDN, Sophia (Author)
  • English (Publication Language)
  • 194 Pages - 02/05/2019 (Publication Date) - Rockridge Press (Publisher)

I get commissions for purchases made through links on this website. As an Amazon Associate I earn from qualifying purchases.